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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRCC All Species: 33.64
Human Site: S481 Identified Species: 67.27
UniProt: Q92733 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92733 NP_005964.3 491 52418 S481 T W S E N K L S R R Q T Q A K
Chimpanzee Pan troglodytes XP_001166951 465 48877 G453 R L L S G Q L G K L Q S K I L
Rhesus Macaque Macaca mulatta XP_001116797 491 52356 S481 T W S E N K L S R R Q T Q A K
Dog Lupus familis XP_851627 489 52096 S479 T W S E N R L S R R Q T Q A K
Cat Felis silvestris
Mouse Mus musculus NP_291051 491 52283 S481 T W S E N K L S R R Q T Q A K
Rat Rattus norvegicus NP_001101170 489 52102 S479 T W S E N K L S R R Q T Q A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423657 512 54438 S502 T W S E N K L S R R Q T Q A K
Frog Xenopus laevis NP_001084270 543 58416 S533 S W S E N K M S R R Q T Q A K
Zebra Danio Brachydanio rerio NP_001119912 392 43164 R383 W A D N K L T R R Q T Q A K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647638 472 51508 T462 M W S A N R Q T R R A T Q S K
Honey Bee Apis mellifera XP_001120938 399 45177 R390 W A Q N R L T R K Q T Q S K Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783288 538 58013 T527 Q W A D N R A T R K S Q N A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.4 99.3 95.3 N.A. 93.6 93 N.A. N.A. 65 53.4 46 N.A. 23 24.4 N.A. 34.5
Protein Similarity: 100 92.6 99.5 97.1 N.A. 95.9 95.5 N.A. N.A. 72.8 63.5 59.2 N.A. 34.6 40.9 N.A. 48.3
P-Site Identity: 100 13.3 100 93.3 N.A. 100 100 N.A. N.A. 100 86.6 6.6 N.A. 53.3 0 N.A. 33.3
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. N.A. 100 100 13.3 N.A. 73.3 13.3 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 9 0 0 9 0 0 0 9 0 9 67 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 9 50 0 0 17 9 0 0 9 17 75 % K
% Leu: 0 9 9 0 0 17 59 0 0 9 0 0 0 0 9 % L
% Met: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 75 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 9 0 0 9 9 0 0 17 67 25 67 0 0 % Q
% Arg: 9 0 0 0 9 25 0 17 84 67 0 0 0 0 0 % R
% Ser: 9 0 67 9 0 0 0 59 0 0 9 9 9 9 0 % S
% Thr: 50 0 0 0 0 0 17 17 0 0 17 67 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 17 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _